Nifedipine ointment anal fissure

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Acta Med Iran. Sep-Oct;48(5) The effect of topical nifedipine in treatment of chronic anal fissure. Golfam F(1), Golfam P, Khalaj A, Sayed Mortaz SS.

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Nifedipine ointment is used to treat anal fissures. This muscle contraction can reduce blood flow to the anus and prevent the fissure from healing. Nifedipine works by relaxing the smooth muscle of the internal anal sphincter so the fissure can heal. Your doctor will prescribe nifedipine as a % ointment. Nov 14, - An anal fissure is a tear in the lining of the anus, the opening where feces Topical nifedipine and topical nitroglycerin — Topical nifedipine.

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Jul 11, - Patients with anal fissures frequently seek care for pain. headache in up to 25% of patients A single study comparing topical nifedipine. With the knowledge that topical nifedipine has been shown to relax smooth muscle, OUTCOMES MEASURED: Healing of the chronic anal fissure was the.

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Mar 10, - Nifedipine—a medication approved as an oral treatment for blood pressure—can reduce internal anal pressure when used in topical gel form. Diltiazem/Nifedipine ointment is used to help heal anal fissures. The ointment relaxes the smooth muscle around the anus and promotes blood flow which helps.

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Mar 15, - Anal fissure is a tear in the squamous epithelium lining the distal anal . anal fissure received treatment with topical nifedipine ointment %. Feb 1, - An anal fissure is a common, mostly benign, condition that can be acute or . topical nifedipine has also shown some encouraging results.

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Apr 15, - Clinical Question: Is a topical gel containing nifedipine and lidocaine effective in the treatment of chronic anal fissures? Setting: Outpatient. Jul 6, - Chronic anal fissure is one of the most frequent anorectal disorders. steps: from topical nifedipine + lidocaine cream (first-line) to second.

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Background: Surgical sphincterotomy for chronic anal fissure can cause fecal incontinence. Topical nifedipine and botulinum toxin injections are an excellent. Comparison 10 Topical CCB (% topical Nifedipine) versus Hydrocortisone . Because of the disability associated with surgery for anal fissure and the risk of.

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Chronic anal fissure is the most common cause of anal pain associated with internal anal sphincter hypertonia. Reduction of hypertonocity is a special treatment. Most anal fissures heal with home treatment after a few days or weeks. . These may include nitroglycerin cream, high blood pressure medicines in pill or gel.

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The current first line of treatment for symptomatic anal fissure is topical nitroglycerin and/or calcium channel blockers such as nifedipine and diltiazem. Anal Fissures: Nifedipine and Diltiazem. When used as a gel directly on the anus, these medicines work as well as nitroglycerin cream. The gel form of these.

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As an alternative to glyceryl trinitrate rectal ointment, chronic anal fissure may also be treated with topical diltiazem hydrochloride 2% [unlicensed] or nifedipine. Anal fissure is a tear in the mucosal lining of the anal canal extending from anal Prescribe topical nifedipine %, twice daily for 3 weeks, or diltiazem gel 2%.

Nifedipine ointment anal fissure

An anal fissure is a break or tear in the skin of the anal canal. Anal fissures may be noticed by In cases of pre-existing or suspected fissure, use of a lubricating ointment (It is important to note that hemorrhoid . "Aggressive Treatment of Acute Anal Fissure with % Nifedipine Ointment Prevents Its Evolution to Chronicity". Jan 31, - efficacy of topical ISDN and nifedipine for chronic anal fissure treatment has been previously demonstrated (14,15). The purpose of the present.

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The aim of this study was to test the efficacy of local application of nifedipine and lidocaine ointment in healing chronic anal fissure. METHODS: The study was. PURPOSE: Nifedipine (administered orally or applied topically) has been effective for nonsurgical treatment of anal fissure. We compared the efficacy of.

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Nov 9, - Oral and topical calcium channel blockers (diltiazem and nifedipine) have been shown to be effective treatment options for anal fissures. Dec 15, - Analogous to the use of NTG intra-anal ointment, nifedipine ointment is also available for use in clinical trials. It is thought to have similar.

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The Effect of Topical Nifedipine in Treatment of Chronic Anal Fissure. Farzaneh Golfam Depatment of Surgery, Mostafa Khomeini Hospital, Shahed University of. ABSTRACT. Objective: To compare the complete healing of chronic anal fissure by using 2% nifedipine paste and % glyceryl trinitrate ointment each applied.